Pharmaceuticals

In the pharmaceutical industry, thermal stability significantly impacts drug efficacy and safety, making thermal analysis an essential analytical tool. DSC is commonly used to measure glass transition, crystallization, and melting of pharmaceutical compounds and formulations. It provides insights into amorphous states, polymorphism, and mechanochemical effects from processing such as drying, grinding, and tableting. TG-DTA enables the assessment of moisture content, solvent evaporation, and decomposition temperatures. When combined with a water vapor generator, material behavior under controlled humidity can also be analyzed. Sample observation analysis captures morphological and color changes, such as transparency variations due to melting and crystallization. Additionally, thermal analysis methods are included in regulatory standards such as the Japanese Pharmacopoeia (JP) and the United States Pharmacopoeia (USP).