Automated Crystal Transport Orientation and Retrieval Robot

Automatic sample mounting, single crystal X-ray screening and data collection

The ACTOR™ system is a proven commercial solution for automating routine crystal screening and data collection at both synchrotron beam lines and home laboratories. Compatible with almost any goniometer and detector combination, the ACTOR 2 builds on the successful ACTOR with a new robotic arm, the Universal Robotics UR5e. The ACTOR system provides a reliable, consistent way to mount samples while at low temperature, and ensures anyone can safely transfer sensitive samples to the goniometer and back. The 4th generation gripper minimizes formation of ice and mimics mounting by hand with cryo tongs such that the sample is immediately bathed in the cold stream of the cryo device when mounted. A robotic sample changer also enables unattended operation for extended periods of time day and night, thus maximising return on investment.

ACTOR 2 Overview

Rapid automatic crystal screening

ACTOR 2 allows you to screen up to 30 samples per hour. Adding automation to your structure solution pipeline also complements the high throughput needed for fragment-based screening projects and structural genomics programs. ACTOR 2 enables you to quickly screen many crystals for optimal diffraction qualities and cryo-conditions and includes ranking software to assist you in comparing samples and finding the best crystals for data collection.

Shorten the crystallization to structure pipeline

ACTOR 2 allows you to effectively shorten the time gap between crystallization and structure solution. ACTOR was the first commercial automated crystal mounting robot and won the 2002 R&D 100 Award for technical innovation. Today over 70 ACTOR robots are in operation in home labs and at beamlines around the world. ACTOR 2 can increase the number and quality of your diffraction experiments, ensuring your success in increasingly competitive funding and IP environments.

ACTOR 2 Features

Completely automated sample mounting, centering and data collection
Integrated sample ranking and data collection strategy algorithms
Choice of dewar base plates for use with either ACTOR, ALS, Uni-Puck sample holders
(Tools and magazines for ALS and Uni-Puck must be purchased separately)
Storage capacity: up to 112 samples per dewar, up to 3 dewars depending on puck system in use

ACTOR 2 Specifications

Technique Automated crystal transport orientation and retrieval robot
Benefit Automatic sample mounting, single crystal X-ray screening and data collection
Technology High-throughput single crystal X-ray diffraction
Attributes Automatic robotic handling
Options Additional Dewars
RFID or barcode sample tracking
Software CrysAlisPro – CAPRobotics module

ACTOR 2 Resources


TOPIQ | The New ACTOR 2 Sample Changer for Automating Your Single Crystal Workflow Watch the Recording


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