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XRD Application to Pharmaceuticals 3. Total Diffraction and Amorphous Material Characterization

X-ray powder diffraction is regarded as the gold standard with respect to the characterization of crystalline solid forms in pharmaceutical materials. However, the traditional Bragg peak crystalline methods become less relevant with the general trends of the increasing complexity of active molecules and the prevalence of non-crystalline forms (amorphous, meso-phasic, nano-phases, etc.).

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