Series of recorded demos of the Progeny Hand-held 1064 nm Raman analyzing from raw material to finished products. Live Q/A with Dr. Suzanne Schreyer.

SmartLab Studio II, the integrated XRD software for both measurement and analysis, is fully compliant with 21 CFR Part 11. The features and how easy to use the software are introduced.

A primary anti-coagulant narrow therapeutic index drug, warfarin sodium, poses a high risk of thrombosis or excessive bleeding with sudden death. The root cause for these risks is not well established. It has been hypothesized that a freely soluble crystalline warfarin sodium (WARC) transforms to non-crystalline warfarin sodium (WARNC) under stress conditions and that the WARNC can later transform to the poorly soluble un-ionized form. This transformation could directly lead to dissolution failure in-vivo and could be responsible for the increased clinical risks. The study presented here focused on systematically characterizing solid form changes and 2-propanol (IPA) content under different environmental conditions followed by a low volume 2-stage dissolution method to mimic in vivo GIT behavior.