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ClpS SAD phasing

AppNote PX023: data collection on the XtaLAB Synergy-S


Rigaku’s XtaLAB Synergy-S is much more than a crystal screening instrument. It comes equipped with a powerful source, an ultrafast kappa goniometer, and a hybrid photon counting detector to enable fast data collections on macromolecular crystals. Here, we show a 30-minute data collection on an orthorhombic crystal of ClpS. The data are complete to 1.28 Å and the structure can be solved by single wavelength anomalous dispersion (SAD).

ClpS SAD phasing with 30 minutes of data collection on the XtaLAB Synergy-S

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