3D structure of large biological molecules
This technique employs single crystal X-ray diffraction (SXRD) to unambiguously determine the three-dimensional structure of large biological molecules. The determination of such molecules gives researchers insight into biology and life at the molecular level. Given the importance of this research, Rigaku has been at the forefront in the development of a wide range of instrumentation related to various aspects of macromolecular crystallography.
One important application is structure-based drug design, a technique by which drugs are designed based on a knowledge of the three-dimensional structure of an enzyme’s active site.
Rigaku recommends the following products:
A new and fully integrated electron diffractometer for measuring submicron crystals, utilizing a seamless workflow from data collection to structure determination of crystal structures
Our most popular diffractometer for Chemical Crystallography and Mineralogy, configured with either single or dual microfocus sealed tube X-ray sources and an extremely low noise direct X-ray detection detector.
Our most popular diffractometer for Protein Crystallography, configured with a high-flux rotating anode X-ray source and an extremely low noise direct X-ray detection detector.
Spectacular performance combined with dual wavelength versatility, provides the perfect answer for high-capacity Chemical Crystallography labs or for X-ray facilities that support Chemical Crystallography and Protein Crystallography.
A bespoke, extremely high-flux diffractometer with custom enclosure and the flexibility to utilize both ports of the rotating anode X-ray source.
Small angle X-ray scattering (SAXS) Kratky camera system.
A curved detector based on direct X-ray detection technology with the highest 2θ range at a single position available for the home lab.
A curved single crystal X-ray diffraction detector based on direct X-ray detection technology with a higher 2θ range compared to a flat detector.
Extremely low noise detector based on direct X-ray detection technology.
High-resolution X-ray detectors for X-ray diffractometers from DECTRIS.
Robotic sample changer to provide unattended data acquisition, enhanced productivity and standardized workflow to your research environment.
Automated tool for performing in situ crystallography experiments on existing X-ray diffractometers.
Automated crystal transport, orientation and retrieval robot specifically designed for high-throughput structural biology.
Single wavelength Confocal Max-Flux (CMF) optics for single crystal diffraction
User-inspired data collection and data processing software for small molecule and protein crystallography.