As research projects multiply and diversify, and chemists attempt the synthesis of ever more exotic molecules, the isolation and crystallization of these molecules for subsequent characterization often represents the bottleneck for advancement of the project. So when crystallographers are presented with a batch of tiny crystals, they must be able to rely on a powerful X-ray diffractometer to collect the data required to elucidate the structure of these new compounds and characterize them without any ambiguity. To address such difficult applications, the Rigaku Oxford Diffraction XtaLAB Synergy-S diffractometer features a powerful 50 watt microfocus sealed tube with a small FWHM beam size of 110 µm, ensuring that most of the X-ray photons are concentrated on the important area, the crystal. In addition, the Rigaku Oxford Diffraction XtaLAB Synergy-S is configured with a HyPix-6000HE hybrid photon counting (HPC) detector. HPC detectors have been used at most synchrotron beamlines around the World because of their high sensitivity and very low electronic noise. These features are also critical to collect precise and accurate data on weakly diffracting crystals on home diffractometers. Here, we demonstrate the performance of the XtaLAB Synergy-S on a tiny organic crystal of benzophenone.
A very small crystal of benzophenone, with dimensions 0.015 x 0.018 x 0.027 mm³, was captured on a MiTeGen Kapton loop mounted on a magnetic base, using paratone oil. The crystal was mounted on the goniometer, centered in the beam using a video camera and data were collected at 100 K with the Rigaku Oxford Diffraction program CrysAlisPro.
A benchtop single crystal X-ray diffractometer with the latest technology HPC X-ray detector, ideal for self-service crystallography.
A microfocus single crystal X-ray diffractometer configured with an HPC direct detection X-ray detector and either one or two microfocus X-ray sources.
A high performance single crystal rotating anode X-ray diffractometer with a low noise direct detection HPC X-ray detector.
A high-flux, versatile X-ray diffractometer with HPC X-ray detector for multipurpose diffraction experiments and small samples
An upgradeable single crystal X-ray diffractometer for structural analysis of small molecule samples
A bespoke single crystal X-ray diffractometer with custom enclosure and the flexibility to utilize both ports of a rotating anode X-ray source.
User-inspired data collection and data processing software for small molecule and protein crystallography
A unique curved single crystal X-ray diffraction detector
Low noise, sensitive, air-cooled X-ray detector for superior X-ray diffraction data quality