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In-house SAD phasing with chromium radiation

AppNote PX007: SAD phasing of protein crystal using chromium radiation

Background

Anomalous scattering with soft X-ray radiation creates new possibilities in phasing for macromolecular crystallography. For example, with CrKα radiation the contribution to the anomalous term from sulfur is doubled compared to that for CuKα. CrKα radiation also improves the strength of anomalous scattering of many other intrinsic elements in macromolecules, like calcium, zinc, and phosphorus, because of increased Δf''. Furthermore, the anomalous scattering of selenium is increased substantially with CrKα.

Protein crystallography products from Rigaku

A customized single crystal X-ray diffraction system that has the capabilities of utilizing both ports of a rotating anode X-ray source.

A microfocus sealed tube single crystal X-ray diffractometer that is low maintenance and perfect for screening and evaluating protein crystals.

A single crystal X-ray diffractometer with high-flux microfocus rotating anode X-ray generator and direct detection, HPC X-ray detector.

A versatile and high-flux dual-wavelength (DW) X-ray diffractometer with an HPC X-ray detector for multipurpose diffraction experiments

Single wavelength Confocal Max-Flux (CMF) optics for single crystal diffraction

Automated tool for performing in situ crystallography experiments on existing X-ray diffractometers

Small angle X-ray scattering (SAXS) Kratky camera system

User-inspired data collection and data processing software for small molecule and protein crystallography

A unique curved single crystal X-ray diffraction detector based on direct X-ray detection technology with the highest 2θ range at a single position available for the home lab.

Extremely low noise, air-cooled X-ray detector based on direct X-ray detection technology.

High-resolution X-ray detectors for X-ray diffractometers from DECTRIS

Automated crystal transport, orientation and retrieval robot

The smallest detachable motorized goniometer head on the market